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章维华

发布日期: 2017-03-03浏览次数:

章维华/教授

个人简介:

南京农业大学教授、博导,BB电子院长,江苏省“青蓝工程”中青年学术带头人,江苏省农用化学化工学会副主任委员。19967月至今,在BB电子从事有机化学的教学科研工作。2011 -2012 年参加江苏省委组织部选派全职地方挂职,任江苏省第四批科技镇长团泰兴团副团长、泰兴市科技局副局长。长期从事有机化学、有机合成的教学和科研工作,目前主要致力于基于天然活性分子为模板的新农药创制研究。先后主持完成国家自然国学基金3项,承担国家重点研发计划项目课题两项,主持或参加省部级项目10余项。发表SCI研究论文40余篇,申请发明专利3项,已授权发明专利1项。 

教学工作:

主讲本科生、研究生有机化学有机合成高等有机化学等理论及其实验课程。奉行教书育人思想,践行教学相长理念,不断更新教学思维,改进教学方法,提高教学质量,多次获教师教学质量综合评价优秀。积极开展教学研究,主持教改项目多项,积极参加专业建设、重点课程,有机化学课程群(专业)教学团队首席教授。主编出版国家级规划、省部级规划《有机化学》、《有机化学学习指导》,及副主编省部级规划教材专著等6本。指导完成本科生国家级SRT项目等10余项,指导本科生毕业论文40余人。 

教材建设:

1.《有机化学》,农业部十三五规划教材,主编,中国农业出版社,2018年9月。

2.《有机化学学习指导》,十五国家规划教材,主编,中国农业出版社,2006年6月。

3.《植物化学》(高锦明主编),国家十三五规划教材,副主编,科学出版社,2017年6月。

4.《农药合成》(宋宝安主编),农业部十三五规划教材,副主编,中国农业出版社,2017年1月。

5.《有机化学》(李楠主编),教育部高等农林院校教学指导委员会推荐示范教材,中国农业大学出版社,2011年1月。

6.《拟除虫菊酯化学》(王鸣华主编),副主编,中国农业科技出版社,2004年10月。 

科研工作(主持项目):

1.“十三五”国家重点研发计划“高效低风险小分子农药和制剂研发与示范”,2018YFD0200100201807-202012。“防控小麦赤霉病候选药剂开发及天然仿生活性分子设计合成及抗菌活性研究” ,任务负责人,70万。

2.    “十三五”国家重点研发计划 “农业生物药物分子靶标发现与绿色药物分子设计”,2017YFD0200500,201707-202012。“天然源化合物设计合成与生物活性筛选” ,任务负责人,50万。

3.    中央高校科研业务费重点专项“基于生物源活性分子先导的新农药创制——合理设计、合成、生物活性与作用机制研究”,KYTZ201604201601~201912 300万。

4.    国家自然科学基金面上项目,新型烯丙基香豆素化合物的设计与合成及其抗菌活性研究,21272116201301-20161280万。

5.    国家自然科学基金面上项目,21072096,新型烯丙基香豆素化合物的设计、合成与抗菌活性研究,201101-20111212万。

6.    国家自然科学基金青年基金,20502011,以osthol为先导的新型香豆素化合物的设计、合成和生物活性研究,200601-20081226万。 

科研工作(发表论文): 

1.    Wenjing Cheng, Yiting Xie, Zhiyu Yang, Yueqing Sun, Ming-zhi Zhang, Yubin Ding* and Weihua Zhang*. General Strategy for in Situ Generation of a Coumarin-Cu2+ Complex for Fluorescent Water Sensing. Analytical Chemistry, 2019, 91, 5817-5823.

2.    Chao Deng*, Yingxin Sun, Yi Ren and Weihua Zhang*. Theoretical Studies on Rh (III)-Catalyzed Regioselective C–H Bond Cyanation of Indole and Indoline. Dalton Trans., 2019, 48, 168-175.

3.    Peng Dai, Xiang Yu, Peng Teng, Wei-Hua Zhang* and Chao Deng*, Visible-Light- and Oxygen-Promoted Direct Csp2‑H Radical Difluoromethylation of Coumarins and Antifungal Activities, Org. Lett., 2018, 20, 6901-6905.

4.    Po Hu, Shaowei Wang, YouJia Wang, Chao Deng* and Weihua Zhang*. Theoretical Studies on Mechanism of Pd2+-Catalyzed Regioselective C-H Acylation of Azoxybenzenes with α-Oxocarboxylic Acids. Dalton Trans. 2018, 47, 14644-14651.

5.    Xiang Yu, Peng Dai, Yu-Chuan Zhu, Peng Teng, Wei-Hua Zhang*, and Chao Deng*Metal-free, Visible-Light-Mediated Direct Csp2-H Radical Mono- and Bis-trifluoromethylation of Coumarins and Bioactivity Evaluation,ChemCatChem, 2018, 10, 5115-5118.

6.    Shu-Guang Zhang, Chao-Gen Liang and Wei-Hua Zhang*, Recent Advances in Indazole-Containing Derivatives:Synthesis and Biological Perspectives, Molecules. 2018, 23, 2783-2824.

7.    Yiting, Xie, Wenjing Cheng, Bing Jin, Chaogen Liang, Yubin Ding* and Wei-Hua Zhang*. Solvent directed Selective and sensitive Fluorescent detection of target ions using a coumarin-pyridine probe. Analyst, 2018, 143, 5583-5588.

8.    Xiang Yu, Peng Teng, Ya-Ling Zhang, Zhao-Jun Xu, Ming-Zhi Zhang, Wei-Hua ZhangDesign, synthesis and antifungal activity evaluation of coumarin-3-carboxamide derivatives, Fitoterapia, 127 (2018), 387–395.

9.    Peng Dai, Kai Luo, Xiang Yu, Wen-Chao Yang, Lei Wu* and Wei-Hua Zhang*, Tert-Butyl Nitrite Mediated Expeditious Methylsulfoxidation of Tetrazole-amines with DMSO: Metal-free Synthesis of Antifungal Active Methylsulfinyl-1H-tetrazole Derivatives, Adv. Synth. Catal., 2018, 360, 468 –473.

10. Yubin, Ding, Shu Zhao, Qingqing Wang, Xiang Yu and Weihua Zhang*. Construction of a coumarin based fluorescent sensing platform for palladium and hydrazine detection. Sensors and Actuators B: Chemical, 2018, 256, 1107-1113.

11. Ming-Zhi Zhang*, Chen-Yang Jia, Yu-Cheng Gu, Nick Mulholland, Sarah Turne, David Beattie, Wei-Hua Zhang*, Guang-Fu Yang, John Clough, Synthesis and antifungal activity of novel indole-replaced streptochlorin analogues, European Journal of Medicinal Chemistry, 126 (2017), 669-674.

12. Jun-Jun Wang, Wei-Jie Si, Min Chen, Ai-Min Lu, Wei-Hua Zhang* and Chun-Long Yang*, Synthesis and Fungicidal Activity of Phenylhydrazone Derivatives Containing Two Carbonic Acid Ester groups, Journal of Pesticide Science, 2017, 42 (3), 1–9.

13. Xiang Yu, Ya Wen, Chao-Gen Liang, Jia Liu, Yu-Bin Ding and Wei-Hua Zhang *, Design, Synthesis and Antifungal Activity of Psoralen Derivatives, Molecules, 2017, 22, 1672-1683.

14. Ling Zhang, Jie Zhu, Jing Ma, Lei Wu* and Wei-Hua Zhang*, Visible-Light-Driven α‑Allenylic C-O Bond Cleavage and Alkenyl C-S Formation: Metal-Free and Oxidant-Free Thiolation of Allenyl Phosphine Oxides, Org. Lett., 2017, 19, 6308-6311.

15. Chao Deng, Hua-Kui Liu, Zhong-Bo Zheng, Lijia Wang*, Xiang Yu, Weihua Zhang*, Yong Tang. Copper-Catalyzed Enantioselective Cyclopropanation of Internal Olefins with Diazomalonates. Org. Lett., 2017, 19, 5717–5719.

16. Chen-Yang Jia, Li-Yong Xu, Xiang Yu, Yu-Bing Ding, Bing Jin, Ming-Zhi Zhang⁎, Wei-Hua Zhang, Guang-Fu Yang, An efficient synthesis and antifungal evaluation of natural product streptochlorin and its analogues, Fitoterapia. 125 (2018) 106–110.

17. Yi-Gang Ji, Kai Wei, Teng Liu, Lei Wu* and Wei-Hua Zhang*, “Naked” Iridium (IV) Oxide Nanoparticles as Expedient and Robust Catalysts for Hydrogenation of Nitrogen Heterocycles: Remarkable Vicinal Substitution Effect and Recyclability, Adv. Synth. Catal., 2017, 359, 933 –940.

18. Ming-Zhi Zhang, Rong-Rong Zhang, Jia-Qun Wang, Xiang Yu, Ya-Ling Zhang,Qing-Qing Wang, Wei-Hua Zhang*, Microwave-assisted synthesis and antifungal activity of novel fused Osthole derivatives, European Journal of Medicinal Chemistry, 124 (2016), 10-16.

19. Rong-Rong Zhang, Jia Liu, Yu Zhang, Meng-Qing Hou, Ming-Zhi Zhang, Fenger Zhou, Wei-Hua Zhang*, Microwave-Assisted Synthesis and Antifungal Activity of Novel Coumarin Derivatives:Pyrano[3,2-c]chromene-2,5-diones, European Journal of Medicinal Chemistry,2016, 116, 76-83.

20. Ming-Zhi Zhang, Yu Zhang, Jia-Qun Wang and Wei-Hua Zhang*, Design, Synthesis and Antifungal Activity of Coumarin Ring-Opening Derivatives, Molecules, 2016, 21, 1387-1398

21.  Fan Zhang*, Xiaoju Yin, Weihua Zhang, Development of magnetic Sr5(PO4)3(OH)/Fe3O4 nanorod for adsorption of Congo red from solution, Journal of Alloys and Compounds657 (2016) 809-817.

22.  Fan ZhangXiaoju Yin Jing LanWeihua Zhang*Application of Ba3(PO4)2/Fe3O4 as a novel magnetic adsorbent to remove methyl blue from aqueous solutionJ Mater Sci (2016) 51:3525–3535.

23.  Fan Zhang, Xiaoju Yin, Weihua Zhang, Yuefei Ji, Optimizing decolorization of methyl blue solution by two magnetic hydroxyapatite nanorods, Journal of the Taiwan Institute of Chemical Engineers. 65 (2016) 269–275.

24.  Wei Shen, Li Guo, Tao Wu*, Weihua Zhang*, Muhammad AbidStabilizing beverage emulsions by regenerated cellulosesLWT - Food Science and Technology. 72 (2016) 292-301.